Quinolines and derivatives

Aromatic organic heterocyclic compounds that contain a benzene ring fused with a six-membered ring that contains one nitrogen atom and five carbon atoms. Includes compounds that are derived from quinolines.

Search Within Results

3,316 – 3,330 of 4,473 results

3,316

Medchemexpress LLC Propidium (iodide) | 25535-16-4 | 99.7% | 5 MG

Propidium Iodide (PI) is a nuclear staining agent that stains DNA. It is an analogue of ethidine bromide, emitting red fluorescence when embedded in double-stranded DNA. PI cannot pass through living cell membranes but can pass through damaged cell membranes to stain the nucleus. It is commonly used in detecting apoptosis or necrosis and in flow cytometry analysis.

Stains DNA
Emits red fluorescence when embedded in double-stranded DNA
Used in detection of apoptosis or necrosis
Commonly used in flow cytometry analysis

Pricing & Availability

3,317

Medchemexpress LLC Propidium Iodide | 25535-16-4 | 99.7% | 500 MG

Propidium Iodide | 25535-16-4 | 99.7% | 500 MG

Pricing & Availability

3,318

Medchemexpress LLC 3,7,4'-Trihydroxyflavone | 2034-65-3 | 99.4% | 270.24 | 1 ML

3,7,4'-Trihydroxyflavone, also known as 5-Deoxykampferol, is a flavonoid compound isolated from the stems of Rhus javanica var. roxburghiana. It exhibits anti-inflammatory and antioxidant properties by scavenging various reactive oxygen species (ROS) and reactive nitrogen species (RNS), and can also cleave DNA in the presence of copper ions.

Isolated from natural sources like Rhus javanica var. roxburghiana.
Functions as an anti-inflammatory agent.
Possesses antioxidant activities.
Capable of scavenging reactive oxygen and nitrogen species.
Can cleave DNA when copper ions are present.

Pricing & Availability

3,319

eMolecules 1227608-04-9 | 7-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | MFCD16659699 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc2cccnc2cc1O | 0.1g | 798867649

7-HYDROXYQUINOLINE-6-CARBOXYLIC ACID | AstaTech | 1227608-04-9 | MFCD16659699 | 189.170 | C10H7NO3 | 95.000 | OC(=O)c1cc2cccnc2cc1O | 0.1g | 798867649

Pricing & Availability

3,320

Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 ML

AL-611 is an HCV NS5B polymerase inhibitor with an EC50 of 5 nM, intended for research use only.

Molecular weight of 614.54.
Purity of 99.93%.
Appears as a solid, white to off-white.
Soluble in DMSO (125 mg/mL).
Store powder at -20°C for up to 3 years.
Store in solvent at -80°C for 6 months, or -20°C for 1 month.
Exhibits CC50 > 100 μM and EC50 0.005 μM in Huh-7 cells.
Involved in a Phase 1 clinical trial for Hepatitis C (NCT03253471).

Pricing & Availability

3,321

Medchemexpress LLC TNF-α (31-45), human | 144796-71-4 | 99.99% | 1667.87 | 5 MG

TNF-α (31-45), human is a potent NF-kB pathway activator and a proinflammatory cytokine that induces necrosis or apoptosis. It stimulates the NF-κB pathway via TNFR2, promoting cancer growth, invasion, and metastasis.

Potent NF-κB pathway activator
Induces necrosis or apoptosis
Stimulates NF-κB pathway via TNFR2
Promotes cancer growth, invasion, and metastasis
High purity (99.99% by HPLC)
Molecular weight of 1667.87
White to off-white solid appearance
Sequence: Arg-Arg-Ala-Asn-Ala-Leu-Leu-Ala-Asn-Gly-Val-Glu-Leu-Arg-Asp
Soluble in water at 50 mg/mL (requires ultrasonic)

Pricing & Availability

3,322

Medchemexpress LLC (S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one | 654059-21-9 | 99.8% | 266.34 g/mol | C14H22N2O3 | 100 MG

BAY 59-9435 (HSL-IN-2) is a potent, selective small-molecule inhibitor of hormone-sensitive lipase (HSL) with an IC50 of 0.023 μM. It exhibits cellular activity (28 nM in 3T3-L1 cells for inhibition of forskolin-stimulated lipolysis) and is supplied as a high-purity solid for research use, with recommended storage conditions to maintain stability.

Potent and selective HSL inhibition (IC50 0.023 μM).
Demonstrated cellular activity in adipocyte assays (28 nM).
High purity suitable for biochemical and cellular studies.
Stable as powder under recommended storage conditions.
Soluble in DMSO for assay preparation.

Pricing & Availability

3,323

eMolecules 125238-99-5 | (2S)-2,4-Diaminobutanoic acid, 4-BOC, 2-FMOC protected | Apollo Scientific | MFCD00151941 | 440.496 | C24H28N2O6 | 97.000 | CC(C)(C)OC(=O)NCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 10g | 650576880

(2S)-2,4-Diaminobutanoic acid, 4-BOC, 2-FMOC protected | Apollo Scientific | 125238-99-5 | MFCD00151941 | 440.496 | C24H28N2O6 | 97.000 | CC(C)(C)OC(=O)NCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O | 10g | 650576880

Pricing & Availability

3,324

Medchemexpress LLC SKA-31 | 40172-65-4 | 99.7% | 200.27 | 50 MG

SKA-31 is a potent potassium channel activator that potentiates endothelium-derived hyperpolarizing factor response and lowers blood pressure. It is suitable for research use only.

Potent potassium channel activator with specific EC50 values for KCa3.1, KCa2.2, KCa2.1, and KCa2.3.
Potentiates endothelium-derived hyperpolarizing factor response.
Lowers blood pressure.
Activates KCa2/3 channels more potently and selectively than other activators.
Not acutely toxic and has good pharmacokinetic properties.
Stimulates KCa3.1 and KCa2.3 in vascular endothelial cells, increasing acetylcholine-induced endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilation.

Pricing & Availability

3,325

Medchemexpress LLC Fmf-06-098-1 | 2769753-07-1 | 98.8% | 1073.76 | 25 MG

FMF-06-098-1 is a multi-target kinase PROTAC degrader that targets degradation kinases such as AAK1, AΒL2, AURKA, AURKB, BUBIB, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDk6, CDK7, CDK9, CHEK1, CSNKID, EPHA1, PER, FGFR1, GAK, IRAK4, ITK, LIMK2, MAP4K2, MAP4K3, MAPK6, MAPK7, MARK4, MELK, PKN3, PLK4, PRKAA1, PTK2, PTK6, RPS6KA4, S1K2, STK35, TNK2, UHMK1, ULK1, and WEE1. The compound is composed of a target protein ligand, a VHL ligand, and a linker.

Store powder at -20°C for 3 years, or 4°C for 2 years.
Store in solvent at -80°C for 6 months, or -20°C for 1 month.

Pricing & Availability

3,326

Apexbio Technology LLC Batimastat (BB-94)(Synonyms: BB-94, Batimastat, MMP inhibitor BB-94), 1mg, CAS: 130370-60-4.

Batimastat (BB-94 CAS 130370-60-4) is a synthetic small-molecule inhibitor targeting matrix metalloproteinases (MMPs) Structurally a polypeptide-like analogue of collagen substrates batimastat contains a peptidic backbone and a hydroxamate moiety that binds the catalytic zinc atom of MMPs It inhibits several MMP subtypes markedly including MMP-1 MMP-2 MMP-3 MMP-7 and MMP-9 with reported IC50 values of 3 4 20 6 and 4 nM respectively In preclinical studies batimastat demonstrates inhibitory effects on tumor growth and angiogenesis across various tumor models including ovarian and colon carcinoma xenografts making it relevant for cancer research and therapeutic development

Pricing & Availability

3,327

Apexbio Technology LLC STF 31 724741-75-7 50mg

STF 31 (CAS 724741-75-7) is a small-molecule inhibitor targeting glucose transporter 1 (GLUT1) with an IC50 of 1 M By antagonizing GLUT1 STF 31 disrupts glucose uptake selectively impairing survival in VHL-deficient renal cell carcinoma (RCC) models that depend on enhanced glycolysis In vitro STF 31 exhibits selective cytotoxicity toward VHL-deficient RCC4 cells while exerting minimal effects on RCC4/VHL controls In vivo administration of STF 31 analogs retards tumor growth in VHL-deficient RCC xenografts without notable toxicity in mice STF 31 is utilized in research to investigate GLUT1-mediated metabolic dependencies and therapeutic vulnerabilities in cancer and neuroinflammatory models

Pricing & Availability

3,328

Medchemexpress LLC LM11A-31 dihydrochloride | 1243259-19-9 | 99.9% | 316.27 | 1 ML

LM11A-31 dihydrochloride is a non-peptide modulator of p75NTR (neurotrophin receptor p75) and an orally active, potent antagonist of proNGF (nerve growth factor). This amino acid derivative demonstrates high blood-brain barrier permeability, effectively blocking p75-mediated cell death. It has been shown to reverse cholinergic neurite dystrophy in mouse models of Alzheimer's disease at mid- to late-stage progression.

Non-peptide p75NTR modulator
Orally active and potent proNGF antagonist
Amino acid derivative
High blood-brain barrier permeability
Blocks p75-mediated cell death
Reverses cholinergic neurite dystrophy in Alzheimer's disease mouse models

Pricing & Availability

3,329

Medchemexpress LLC Bay 59-9435 | 654059-21-9 | 99.8% | 266.34 g·mol⁻¹ | C14H22N2O3 | 25 MG

BAY 59-9435 is a potent, selective small-molecule inhibitor of hormone-sensitive lipase (HSL) with a reported IC50 of 0.023 μM. It is used as a research tool to study HSL-dependent lipolysis in cellular and animal models. Not for human or clinical use.

Potent, selective inhibition of hormone-sensitive lipase.
Low IC50 (0.023 μM) enabling submicromolar activity.
High purity suitable for biochemical and cellular assays (99.8%).
Characterized chemical profile (C14H22N2O3; MW 266.34 g·mol⁻¹).
Convenient small pack size for preclinical research (25 mg).

Pricing & Availability

3,330

Medchemexpress LLC SLF-amido-C2-COOH 10mg | 1092369-24-8 | 10MG

SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) is a synthetic ligand for FKBP (SLF) SLF-amido-C2-COOH (PROTAC FKBP12-binding moiety 1) can be used in the synthesis of PROTACs[1

Pricing & Availability

Quinolines and derivatives

Filtered Search Results

Narrow Results

Medchemexpress LLC Propidium (iodide) | 25535-16-4 | 99.7% | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Propidium Iodide | 25535-16-4 | 99.7% | 500 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC 3,7,4'-Trihydroxyflavone | 2034-65-3 | 99.4% | 270.24 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC AL-611 | 2481279-61-0 | 99.9% | C25H33F2N6O8P | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC TNF-α (31-45), human | 144796-71-4 | 99.99% | 1667.87 | 5 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC (S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one | 654059-21-9 | 99.8% | 266.34 g/mol | C14H22N2O3 | 100 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SKA-31 | 40172-65-4 | 99.7% | 200.27 | 50 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Fmf-06-098-1 | 2769753-07-1 | 98.8% | 1073.76 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC Batimastat (BB-94)(Synonyms: BB-94, Batimastat, MMP inhibitor BB-94), 1mg, CAS: 130370-60-4. Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Apexbio Technology LLC STF 31 724741-75-7 50mg Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC LM11A-31 dihydrochloride | 1243259-19-9 | 99.9% | 316.27 | 1 ML Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC Bay 59-9435 | 654059-21-9 | 99.8% | 266.34 g·mol⁻¹ | C14H22N2O3 | 25 MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More

Medchemexpress LLC SLF-amido-C2-COOH 10mg | 1092369-24-8 | 10MG Small and Specialty Supplier PartnerSmall and/or specialty supplier based on Federal laws and SBA requirements.Learn More